BASE PAIR BIOTECHNOLOGIES INC

Base Pair Biotechnologies, Inc. is a world-leading provider of highly customized aptamer discovery and development services. The company is five years old, privately held, and located in the Houston, Texas metropolitan area, close to major medical centers and universities. Technology Base Pair’s intellectual property portfolio includes more than two dozen issued and pending patents as well as trade secrets related to aptamer selection, aptamer screening, and aptamer sequences. Base Pair’s patented multiplex selection process reduces time and cost for aptamer discovery and facilitates development of specific- and pan-binders to related targets. Base Pair also has proprietary aptamer libraries that contain novel modifications, modulating binding properties and increasing conformational diversity. Base Pair has several proprietary techniques for developing aptamers to small molecules and uses novel methods for determining solution phase affinity.